Lindsay Dresang, Ph.D.
Assistant Professor of Biology Office:
(715) 346-3624Email: LDresang@uwsp.edu
2010-2013: University of Pittsburgh Cancer Institute
Post-Doctoral Fellow in the Chang-Moore Lab
2005-2010: University of Wisconsin–Madison, School of Medicine and Public Health
Ph.D. in Cancer Biology
Graduate Research in the Sugden Lab
2003-2005: University of Wisconsin–Madison, College of Agricultural Sciences
B.S. in Natural Sciences, Genetics
Undergraduate Research in the Weichert Lab
2001-2003: University of Wisconsin–Fox Valley (University of Wisconsin–Oshkosh dual enrollment spring 2002)
Bio 160 – Introduction to Animal Biology
Bio 381 – Animal Physiology (Lab Instructor)
Bio 385 – Human Physiology (Lab Instructor)
Bio 387 – Human Anatomy
Bio 399 – Human Anatomy, Teaching Assistant (Independent Study)
Bio 487 – Survey of Human Dissection
Bio 490 – Senior Seminar in Cancer Biology
Bio 490 – Senior Seminar in Virology
Professional Affiliations & Honor Societies
Faculty of 1000 Prime, Peer Reviewer (F1000)
Gamma Sigma Delta, Honor Society in Agricultural Sciences (ΓΣΔ)
Phi Theta Cappa, Two-year Colleges Honor Society (ΦΘΚ)
Cancer Biology: (under construction)
My research goals are to address how select cancer cell lines are prone to metastasize to the liver in an immunocompromised mouse model. There are hundreds of different types of cancers because there are hundreds of types of differentiated cells in the human body. Within the same cancer type, there can be considerable variation between individual tumors in terms of malignancy and metastatic potential. I am interested in assessing multiple cancer types using paired sets of individual cancer cell lines which either do or do not metastasize to the liver in immunocompromised mouse models. Using several cancer cell types with this metastatic / non-metastatic pairing should allow me to assess which cell signaling pathways may influence metastatic potential. Slowing metastatic progression may not eliminate cancer, but it could help stabilize the disease.
Teaching-As-Research: (under construction)
Students may serve as teaching assistants in Human Anatomy (Bio 399) during fall semesters, and possibly over the last 6-week session in summer. Students must have earned at least a B in Human Anatomy to serve as a Bio 399–Human Anatomy TA. Students may then have the opportunity to design a project assessing student learning and/or student appreciation of Human Anatomy.
||Dresang LR, Guastafierro A, Arora R, Normolle D, Chang Y, Moore PS. Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Mouse Xenografts Respond to YM155 Treatment in a Dose, Duration, and Cell Line Dependent Manner. PLoS One 8(11):e80543.
||Dresang LR, Teuton JR, Feng H, Jacobs JM, Camp DG 2nd, Purvine SO, Gritsenko MA, Smith RD, Sugden B, Moore PS, Chang Y. Coupled Transcriptome and Proteome Analysis of Human Lymphotropic Tumor Viruses: Insights on the Detection and Discovery of Viral Genes. BMC Genomics 12(625).
||Dresang LR, Vereide DT, Sugden B. Identifying Sites Bound by Epstein Barr Nuclear Antigen 1 (EBNA1) in the Human Genome: Defining a Position-Weighted Matrix to Predict Sites Bound by EBNA1 in Viral Genomes. J Virol 83(7):2930-2940.
|Faculty of 1000 Reviews:|
||Moore PS, Feng H, Dresang LR. Decoding human cytomegalovirus.
||Moore PS, Dresang LR. Direct and efficient cellular transformation of primary rat mesenchymal precursor cells by KSHV.
||Moore PS, Dresang LR. Discovery of a viral NLR homolog that inhibits the inflammasome. |