This is Figure 17.6 from Garrett, R.H.; Grisham, C.M. Biochemistry; Saunders: Orlando,1995; page 553. (a) Separate enzymes with freely diffusing pathway intermediates, such as glycolysis. (b) Cytosolic multienzyme complex with intermediates channelled between enzymes, such as pyruvate dehydrogenase complex. (c) Membrane bound multienzyme complex, such as the electron transport system.